Basic concepts of chemical and biological engineering systems. Modeling through material and energy balances. Problem solving methods, computational techniques and computer simulation. Examples from chemical and pharmaceutical industries.

Protein characterization, enzyme kinetics, basic metabolic pathways, membrane structure and function, biochemistry of energy and signal transduction, replication and expressions of genes. Labaratory studies.

Experimental demonstration of concepts taught in separations, reaction engineering and control.

Chemical process and product design methods; economic analysis of chemical processing plants.

Biotechnology course with a strong emphasis on bioprocess engineering principles. Fermentation, mammalian cell culture, continuous culture, biological unit operations, lectures on synthetic biology topics. Strongly recommended for CHBI students that wish to design a biological process in CHBI 491.

Reconstruction of metabolic network from genome information and its structural and functional analysis, computational models of biochemical reaction networks; system biology in drug discovery and proteomics, flux balance analysis; modeling of gene expression; system biology in artificial intelligence.

Fundamental principles and advantages of drug delivery technologies; drug delivery mechanisms; advantages of controlled delivery; administration routes; drug delivery agents; possible modifications of delivery vehicles for specific applications.

A capstone design course where students apply engineering and science knowledge in a chemical and biological engineering design project. Development, design and management of a project in teams under realistic constraints and conditions. Emphasis on communication, teamwork and presentation skills.

Fluids classification; transport coefficients; momentum transfer and velocity profiles; energy and mass transfer for isothermal and multicomponent systems; mass transfer with chemical reaction; applications for chemical and biological systems.

Kinetics of homogeneous and heterogeneous chemical reactions; catalysts; design of chemical reactors; applications for chemical and biological systems.

Classical thermodynamics: enthalpy, entropy, free energies, equilibria; introduction to statistical thermodynamics to describe the properties of materials; kinetic processes; diffusion of mass, heat, energy; fundamentals of rate processes in materials, kinetics of transformations.

Biotechnology course with a strong emphasis on bioprocess engineering principles. Fermentation, mammalian cell culture, continuous culture, biological unit operations, lectures on synthetic biology topics. Strongly recommended for CHBI students that wish to design a biological process in CHBI 491.

Reconstruction of metabolic network from genome information and its structural and functional analysis, computational models of biochemical reaction networks; system biology in drug discovery and proteomics, flux balance analysis; modeling of gene expression; system biology in artificial intelligence. These concepts will be supported with statistic, thermodynamic, structural biology and learning machine

Fundamental principles and advantages of drug delivery technologies; drug delivery mechanisms; advantages of controlled delivery; administration routes; drug delivery agents; possible modifications of delivery vehicles for specific applications.

Atomic structure, chemical bonds, compounds, solutions, stoichiometry. Electrochemistry, thermodynamics, kinetics, acids and bases, basic organic chemistry.

Atomic and molecular structure, spectroscopy, stoichiometry, chemical thermodynamics, electrochemistry, structure and properties of materials.

Basics of general chemistry and introduction to quantum mechanics including chemical bonding, molecular structure, states of matter and phase transitions, intermolecular interaction, chemical equilibrium, thermodynamics / thermochemistry, acid-base equilibria, materials chemistry and spectroscopy.

Basic principles and units of measurement, S.I. unit for chemical quantity, units of concentration, gravimetric methods of analysis, volumetric methods, titration of polyprotic acid and bases, complexation and pricipitation titrations, elements of electrochemistry, oxidation-reduction titration, electrolysis, potentiometry, conductomery, introduction to analytical separations: column chromatography. Thin layer chromatography, analysis of chromatograms, high performance ion-exchange chromatography.

Bonding, molecular shapes and stereochemistry in organic compounds. Functional groups, reactivity and mechanisms of basic organic reactions, such as nucleophilic and electrophilic substitution, elimination and addition. Principles of organic synthesis, critical reaction parameters and their optimization. Carbonyl compounds, amines, phenols and their reactions. Synthetic polymers and their applications.

Bonding, molecular shapes and stereochemistry in organic compounds. Functional groups, reactivity and mechanisms of basic organic reactions, such as nucleophilic and electrophilic substitution, elimination and addition. Principles of organic synthesis, critical reaction parameters and their optimization. Carbonyl compounds, amines, phenols and their reactions. Synthetic polymers and their applications. Prerequisites : CHEM 102 or consent of the instructor.

Properties of perfect and real gases, the first and second laws of thermodynamics, entropy, free energy, physical transformations of pure materials and simple mixtures, the phase rule and phase diagrams, chemical equilibrium. Lab component.

Quantum mechanics, solution of the particle-in-a-box, harmonic oscillator and hydrogen atom; orbital concepts, the structure of many-electron atoms, molecular orbital theory, molecular symmetry and group theory; rotational, vibrational and electronic spectroscopy.