Integration of the knowledge from different areas of the business curriculum: operations, marketing, accounting, finance, information systems, management strategy by applying concepts and frameworks to real life cases to solve business problems; teamwork and presentations.

Integration of the knowledge from different areas of the business curriculum: operations, marketing, accounting, finance, information systems, management strategy by applying concepts and frameworks to real life cases to solve business problems; teamwork and presentations.

Integration of the knowledge from different areas of the business curriculum: operations, marketing, accounting, finance, information systems, management strategy by applying concepts and frameworks to real life cases to solve business problems; teamwork and presentations.

Theoretical and practical aspects of working in a cell culture laboratory. Maintenance of a cell culture laboratory; problems and solutions.

The importance of genetic makeup in controlling and shaping an organism and disease-causing mutations in the human genome. Historical milestones of gene editing from viral therapy to CRISPR/Cas9. Scientific processed behind the discovery of CRISPR-systems. In-depth discussion of the relevant scientific papers.

Micro and nanoscale biological systems and their applications in regenerative medicine, disease modeling, diagnostics and therapy. Properties of micro and nanoscale building blocks, their assembly processes and their use in synthesizing larger systems to address biological problems. A plethora of biological and chemical structures, design of systems for use in sensing and diagnosing biological phenomena, manipulating cell functions, engineering tissues, modeling pathologies and delivering therapeutics. Bioinspired and biomimetic design of microphysiological systems, tissues and organ-on-a-chip approaches. Technological impact and use of such systems in translational research.

How rare genetic disease help to understand common diseases, from clinical to in vitro approaches. Genetic to potential causative gene: Description of the essential steps that allow to identify potentially disease-causing genes. How to detect rare mutations: Overview of next generation sequencing technologies. From patients to dish: Generation of primary tissue/cells, culture and storage. How to prepare tools for modeling: Molecular genetic assays: expression cloning, transfection, mutagenesis, gene editing KO/KI. Biochemistry techniques: Western blot, fractionation, Immunoprecipitation. Cells based assay: Viability, proliferation, cytotoxicity, senescence and cell death assays. Power of tissue and cells imaging: Immunofluorescence, histology, confocal, electron microscopy, live imaging. Advantage of Omics techniques: Transcriptomics, Proteomics, Metabolomics. At the bench: Culture and biochemistry techniques. Modeling Neurodegeneration. Cancer In vitro Modeling. From bench to therapeutic: High throughput cellular assay to drug development.

Aim: to learn the basic concepts of cancer metastasis and recurrence. Introduction to cancer biology and metastasis, cancer stem cells, epithelial mesenchymal transition (EMT), mechanisms of cancer cell migration, mechanisms of cancer cell survival and death, mechanisms of tissue invasion, intravasation and survival in the circulation, metastasis through lymphatics, metastasis to lymph nodes, autophagy and cancer, tissue tropims and metastasis, cancer recurrence/relapse.

Students will attend seminars on the new developments and applications related to cellular and molecular medicine throughout the semester. The students will provide summary reports on 6 of these seminars to the program coordinators.

The aim of the course is to give students experience in selected methods used in cellular and molecular medicine. The course comprises of a theoretical lecture closely integrated with practical experimentation. The hands on practical classes will enable the student to learn the techniques and experimental strategies of modern biochemical and molecular biological research. Macromolecules that are covered are proteins and DNA. Methods utilized are; purification of macromolecules, chromatography, gel electrophoresis, protein quantification, application of antibodies, propagation of plasmids in bacteria, isolation and characterization of plasmid DNA, introduction of genes into mammalian cells and observation of protein expression in cells.

This course is non-credit and aims to increase the scientific interaction between students and improve their presentation skills with the participation of students from all interdisciplinary programs. The Seminar course which is consisting of presentation of the studies and researches in front of the community within the framework of the techniques determined with the guidance of the advisor, and question and answer part are graded each semester.

History and scope of Chemical and Biological Engineering and its interaction with other disciplines, Teaching objectives of Chemical and Biological Engineering, Engineering Design Principles and Applications in Chemical and Biological Engineering ( Design of Experiments, Design of Processes, Design of Products, From Genes to Products.

To give qualified Chemical and Biological Engineering students a unique opportunity to teach as a part of their undergraduate experience; to give responsibility for running review and problem sessions, holding office hours and supervising laboratories for Chemical and Biological Engineering area courses.

First and second laws. Energy conservation and entropy. Analysis of engineering systems, such as refrigeration cycles and combustion engines. Vapor/liquid equilibrium,applications in mixture behaviours.

Characteristics of fluids, fluid statics, Bernoulli equation, fluid kinematics, boundary layers, viscous flows and turbulence.

Theory of rate and equilibrium based separation operations for separating mixtures. Distillation, absorption and extraction, Chromatography, ion exchange, membrane separations, electrophoresis. Multicomponent separations.

Design and operation of chemical reactors. Homogeneous, heterogeneous and biochemical reactions. Ideal and non-ideal reactors. Kinetics of enzyme-catalyzed reactions. Kinetics of substrate utilization and biomass production.

Dynamic models for chemical and biological systems. Their simulation and analysis. Design and implementation of control systems.

Polymers, their synthesis and properties. Relationshios between molecular structure and properties. Rheology in polymer processing. Fabrication methods and applications.

The principles and computational methods to study the biological data generated by genome sequencing, gene expressions, protein profiles, and metabolic fluxes. Application of arithmetic, algebraic, graph, pattern matching, sorting and searching algorithms and statistical tools to genome analysis. Applications of Bioinformatics to metabolic engineering, drug design, and biotechnology.

Recombinant DNA, enzymes and other biomolecules. Molecular genetics. Commercial use of microorganisms. Cellular reactors; bioseparation techniques. Transgenic systems. Gene therapy. Biotechnology applications in environmental, agricultural and pharmaceutical problems.

Electrochemical thermodynamics, kinetics and mass transport; electrode structures; batteries and battery pack design; fuel cells and system and stack design; electrochemical double layer capacitors; electrolyzers; design and modelling of electrochemical reactors.

The fundamentals of tissue engineering at the molecular and cellular level; techniques in tissue engineering; problems and solution in tissue engineering; transplantation of tissues in biomedicine using sophisticated equipments and materials; investigation of methods for the preparation of component of cell, effect of growth factors on tissues.