Offers a broad introduction to the growing corpus of literature on the body. Draws on novels, theatrical plays and films across a range of cultural locations and over a broad chronological span from the Renaissance to the present. Considers the ways in which bodily representations reflect social and political attitudes about class, race, gender, and sexuality, and how these attitudes change across different historical periods. Explores the politics of bodily representation in a historicist way and provides a basic introduction to key literary periods.

Exploring the innovation and creative processes through interdisciplinary work and research structures. Understanding design problems independent from their disciplinary boundaries. Gaining an integrative understanding of innovation based on human-centered design.

Looking at the Turkish History, Culture and Society during Republican times through the lens of movies. Analyzing relationships between different elements of society with a historical perspective and with historical realities. Major themes, such as minorities, urbanization, Islam and gender relations will be covered.

To develop ability to express the significance of different literary forms as a reflection of sensory experience. Questions how different genres of literature portray the world as shaped by sense perceptions and how these perceptions might become ideological tools through discussions of gender, race or class. Asks the role of sensory skills in the way life is experienced. Raises up ethical issues concerning people with sensory loss asking students to relate their own experiences to situations presented in texts. Develops awareness of the immediate world around students through creative writing tasks like reporting the sounds or smells of a street. Includes 20th century literary works in English and Turkish with support from other disciplines such as philosophy, psychology, cultural studies and visual arts.

Explores the relationships between medicine, healthcare practices, the human body, and visual culture from Ancient Mesopotamia to present day Türkiye. An introduction to visual medical and health humanities, the human condition is examined using diverse works of art drawn from different eras, geographies, stylistic and cultural movements. Develops skills of critical observation, description, and creativity by studying works from the history of art that highlight medicine, healing, and healthcare.

Historical intersections of music and politics. Music and lyrics against the political historical background of select countries from all continents. Music for political propaganda and protest.

Introduction to Law; Public Law; Private Law; Introduction to Turkish Law (Turkish Judicial System; Constitutional Law; Administrative Law; Criminal Law; Criminal Procedure) History of Turkish Private Law; Basic Concepts of Private Law; Law of Persons; Law of Contracts; Sales Contracts; Law of Torts; Law of Property; Business Enterprises; Negotiable Instrument; Secured Transactions; Corporate Law; Corporate Taxation; Competition Law; Intellectual Property Law; International Commercial Arbitration; Labour Law.

Integration of the knowledge from different areas of the business curriculum: operations, marketing, accounting, finance, information systems, management strategy by applying concepts and frameworks to real life cases to solve business problems; teamwork and presentations.

Integration of the knowledge from different areas of the business curriculum: operations, marketing, accounting, finance, information systems, management strategy by applying concepts and frameworks to real life cases to solve business problems; teamwork and presentations.

Integration of the knowledge from different areas of the business curriculum: operations, marketing, accounting, finance, information systems, management strategy by applying concepts and frameworks to real life cases to solve business problems; teamwork and presentations.

Theoretical and practical aspects of working in a cell culture laboratory. Maintenance of a cell culture laboratory; problems and solutions.

Information regarding cell structure and function, cell signaling, vesicular trafficking, cell-division cycle, and extracellular matrix. Introduction to cell signaling, G-protein coupled receptors, TGF-beta family members and cytokine receptors, receptor tyrosine kinases, pathways involving proteolysis, ingtegration of signals and gene controls, cell division and cell cycle, membrane trafficking, cytoskeleton, cancer and presentations.

Applied aspects of molecular biology. Introduction and explanation of what is molecular biotechnology as a scientific discipline, which tools of recombinant DNA technologies are applied, and industrial microbiology. The development of molecular biotechnology, DNA, RNA, and protein synthesis, recombinant DNA technology, chemical synthesis, amplification, and sequencing of DNA, bioinformatics, genomics and proteomics, heterologous protein production in eukaryotic cells, directed mutagenesis and protein engineering, protein therapeutics, nucleic acids as therapeutic agents, vaccines, synthesis of commercial products by recombinant microorganisms, transgenic animals, molecular biotechnology and society.

Mechanisms by which cells respond to external physical forces (tension, compression, shear, pressure) and relevant signaling processes involved in development, regeneration and pathology (i.e. cancer); mechanisms of cell-matrix interactions and physical stimuli-mediated cellular processes such as tissue remodeling. Cell cytoskeleton and mechanics, ECM and cell-matrix interactions, cellular responses to external physical stimuli, cellular responses to external physical stimuli, mechanobiology in development, mechanobiology in regeneration and tissue remodeling, mechanobiology in disease, analysis of cell mechanics, Manipulation of cell mechanics, applications of mechanobiology.

How rare genetic disease help to understand common diseases, from clinical to in vitro approaches. Genetic to potential causative gene: Description of the essential steps that allow to identify potentially disease-causing genes. How to detect rare mutations: Overview of next generation sequencing technologies. From patients to dish: Generation of primary tissue/cells, culture and storage. How to prepare tools for modeling: Molecular genetic assays: expression cloning, transfection, mutagenesis, gene editing KO/KI. Biochemistry techniques: Western blot, fractionation, Immunoprecipitation. Cells based assay: Viability, proliferation, cytotoxicity, senescence and cell death assays. Power of tissue and cells imaging: Immunofluorescence, histology, confocal, electron microscopy, live imaging. Advantage of Omics techniques: Transcriptomics, Proteomics, Metabolomics. At the bench: Culture and biochemistry techniques. Modeling Neurodegeneration. Cancer In vitro Modeling. From bench to therapeutic: High throughput cellular assay to drug development.

Biochemical changes in mitochondrial diseases metabolism, alteration of certain enzyme activities, shuttles, biochemical mitochondrial markers. Mitochondria, role of Mitochondria in metabolism, role of mitochondria in energy metabolism, mitochondria and aging, mitochondria and oxidative stress, mitochondria and cell death, guidelines on experimental methods on mitochondria, mitochondrial diseases, manuscript and Review presentation.

Aim: to teach the biochemical changes in cancer metabolism, alteration of certain enzyme activities, hormones and growth factors, biochemical tumor markers. A biochemical approach to the cancer cell, carbohydrate metabolism in cancer, differences of glycolysis in cancer cell and healthy cell, pentose phosphate pathway in cancer cells and healthy cells, tricarboxylic acid cycle in cancer cells and healthy cells, fatty acid metabolism in cancer cells and healthy cells, Impact of fatty acid metabolism on the cancer cells correlated with cell signaling, biochemistry of cell signaling, cell signaling pathways, a biochemical approach to cancer metastasis.

Aim: understanding database systems concepts and possess the knowledge about how to use available biological databases and data analysis tools efficiently. Biological databases, database creation and management, introduction to commonly used analysis tools. Extensive use of different biological data types and data formats, biological data editing techniques, Disease-centric databases, data processing and data analysis tools, web-based bioinformatics environments for research and analysis of biological data.

To imitate the physiological, pathological and extracellular matrix characteristics in health and diseases in in vitro. Introduction to 3D culture systems. Applications of 3D cultures in health and disease. Applications of different synthetic and natural hydrogels for 3D culture. Methods to experimental design of 3D culture systems. Organoids and tissue models. Methods to generate spheroids in in vitro. Blood-brain barrier and neuromuscular junction and neural communication models in 3D cultures. Multiplex cell culture approaches in 3D systems. Drug delivery methods for 3D systems. Microfluidic and organ-on-chip systems.

Learning basic concepts and translational applications in the Cell Death Research Field. Introduction to Cell Death Mechanisms, Programmed Cell Death or Cellular Suicide. Apoptosis-Caspases. Apoptosis-Extrinsic Pathway and death receptors. Apoptosis-Bcl-2 family members. Apoptosis-Intrinsic Pathway and Mitochondria. Autophagic cell death. Autosis, Necroptosis. Atypical Cell Death Mechanisms-Anoikis-Mitotic catastrophe. Atypical Cell Death Mechanisms-Ferroptosis-Entosis. Atypical Cell Death Mechanisms- Parthanatos-Pyroptosis.

Students will attend seminars on the new developments and applications related to cellular and molecular medicine throughout the semester. The students will provide summary reports on 6 of these seminars to the program coordinators.

This course is non-credit and aims to increase the scientific interaction between students and improve their presentation skills with the participation of students from all interdisciplinary programs. The Seminar course which is consisting of presentation of the studies and researches in front of the community within the framework of the techniques determined with the guidance of the advisor, and question and answer part are graded each semester.